In 1253, Nichiren Shonin landed at Yonegahama on the Miura Peninsula while traveling from Boso to Kamakura. The local lord Ishiwatari Norihisa, moved by his teaching, built a Lotus hall there — laying the foundation of Daimyoji. Yonegahama is revered as the first sacred site of Nichiren Buddhism on the Miura Peninsula, and this temple preserves that spiritual origin.

Nichijun, the son of Ōta Dōkan, became the 11th abbot of Daimyoji and later rose to become the 13th head of Honkoku-ji, the general head temple of Nichiren Buddhism in Kyoto. Dōkan's eldest son, Ōta Sukeyasu, fought alongside the Miura clan against Hōjō Sōun's advance in 1512 and was killed in battle. His remains are said to be buried at Daimyoji, bearing witness to the deep bond between the Dōkan lineage and this temple.