In 1639, Iemitsu banned Portuguese ships, completing the sakoku isolation policy after the Christian-led Shimabara Rebellion of 1637 hardened the shogunate’s fears. Trade continued only with the Dutch and Chinese at Nagasaki’s Dejima, plus limited contact via Tsushima, Satsuma, and Matsumae. Isolation brought over 200 years of peace and distinctive culture, but left Japan behind in Western science.