The third head of the Later Hōjō clan during the Sengoku period. Inheriting from his father Ujitsuna, he aggressively expanded Hōjō territory toward dominance of the Kantō region. In 1545, at the Battle of Kawagoe, he achieved one of Japan's most stunning military reversals: routing a coalition force of roughly 80,000 (under Uesugi Tomosada, Uesugi Norimasa, and Ashikaga Haruuji) with only 8,000 troops in a night attack. He simultaneously contended with Takeda Shingen, Uesugi Kenshin, and Imagawa Yoshimoto, using diplomacy and stratagem to maximize Hōjō territory. Equally skilled in governance, he reduced tax burdens on retainers, systematized land surveys, and implemented a 40/60 tax split favoring farmers, earning him the reputation of a benevolent administrator. He fortified Odawara Castle into a virtually impregnable stronghold. He died in 1571 at 57, passing leadership to his son Ujimasa.