Born in 1275, from the Nagoe collateral branch of the Hojo clan, a great-grandson of Hojo Yoshitoki. He had served in shogunate offices including the hyojoshu since his early years, building practical experience in administration. He became the tenth regent in 1301 as the ninth regent Sadatoki retreated into dissipation. However, Sadatoki as the tokuso head retained all real power even after taking Buddhist vows, and Morotoki's position was entirely nominal. Day-to-day governance was directed by uchikanrei figures such as Nagasaki Enki and Nagasaki Takasuke. Within these structural constraints, Morotoki conscientiously fulfilled his duties, helping maintain internal order and administrative continuity. In 1311, both Morotoki and the ninth regent Sadatoki died—Morotoki at only 37. Their deaths in the same year created a new power vacuum and set the stage for Hojo Munenobu's appointment as the eleventh regent. Short-lived but diligent, he faithfully occupied the nominal summit of shogunate authority at the height of tokuso autocracy.